ABSTRACT
Aim: Development of commercial hybrid of sunflower on basis of best inbred combination remains a key challenge to sunflower breeders. In the current investigation, heterosis of F1 hybrids, parental genetic diversity and correlation between genetic distance and level of heterosis were estimated. Methodology: Thirty five parental genotypes (3 CMS A lines and 32 R lines) and their hybrids were assessed for physio-morphological, yield and quality traits. Heterosis was measured as mid-parent and better parent heterosis. Among parents, SSR marker based genetic distances were calculated using DARwin software. Correlation between heterosis and genetic distances was carried out by Karl Pearson’s simple correlation method. Results: Range of genetic distances, based on SSR marker analysis, varied from 0.32-0.73. Genetic distance had significant positive correlation with the heterosis for oil content (r = 0.22 p<0.05) and linoleic acid (r = 0.32 p<0.05), but negative correlation was observed for days to maturity, test weight, volume weight, stearic acid and oleic acid. There was no significant correlation between genetic distance and heterosis for seed yield and other agronomic traits. Interpretation: Although, genetic distance is poor predictor of heterosis, dependence of oil content on genetic distance among parental lines may be used for designing an effective breeding program for sunflower.
ABSTRACT
E.C.G is the most widely used test for both the diagnosing and estimating the prognosis of CAD. ST segment and T wave changes are most commonly evaluated parameters of E.C.G. Atorvastatin have found to decrease ischemic events apart from its hypolipidemic effect. The main objective of this open prospective randomized, controlled study was to evaluate the effect of addition of atorvastatin to conventional antianginal treatment on ST segment and T wave changes on E.C.G. The study was conducted for duration of 2 months in 30 patients of CAD (15 in each group). Group A was started on conventional antianginal treatment and group B was started on Atorvastatin 20 mg once a day at night in addition to conventional treatment. The ECG changes were recorded after 15, 30, 45 and 60 days using 12 lead E.C.G. At the end of the study, no significant difference was found in E.C.G changes between the group A and group B. A slight improvement in ST segment changes in group B patients was observed but the effect was statistically not significant. So, addition of atorvastatin to conventional antianginal treatment did not have a significant effect on reversal of ischemic changes on ECG in patients of CAD.